Steelmaker Corus is believed to be axing 366 jobs at its Scunthorpe site in North East England.
The company has said that it has "announced proposals to improve the competitiveness of its Scunthorpe site by aligning costs with anticipated steel demand".
Consultations with employees and their representatives have begun on the site today.
The company said it will seek voluntary redundancies, while at the same time ensuring that critical skills are retained.
Support packages will be available to those leaving the company.
Michael Leahy, general secretary of the steelworkers' union Community, said the latest job cuts added "insult to injury" for the workforce.
He added: "We keep hoping the job losses are ending and then another announcement comes along.
"We were disappointed an agreement could not be reached that would prevent job losses. Unfortunately, Corus did not put all their cards on the table during the negotiations.
"In the coming months, Community will be supporting our members throughout the consultation period and opposing hard redundancies.
"What Corus needs to prove is that these cuts will make steelmaking in Scunthorpe fit for the future, not fit for the scrapheap."
It is understood managers and administrative workers will be hit by the latest job cuts.
For more information visit:Corus May Be Forced To Close Teeside Plant
(CD/JM)
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