Construction work has commenced to transform Northfleet Embankment in Ebbsfleet with 598 new homes.
Along with housing, the development will include a new primary school, local amenities, open space and a Fastrack bus connection.
Keepmoat Homes has agreed a deal with Homes England to deliver the project, after planning permission was granted last year.
Tim Beale, Chief Executive of Keepmoat Homes said: "As Homes England's largest delivery partner, we've worked together to deliver over 11,000 quality new homes across the country as part of consecutive Delivery Partner Panels since 2009.
"We are delighted to have completed this new deal with Homes England and are looking forward to starting on site at this transformational development in Northfleet, where we will create a thriving new community on the banks of the River Thames that is only 20 minutes from central London via Ebbsfleet International station."
The first homes at Northfleet Embankment are expected to be complete by May 2020, with the rest of the development anticipated by 2025.
As part of the deal, Keepmoat Homes has agreed to build the homes at an accelerated rate of over 100 units per year.
A total of 224 homes will be affordable.
This project is part of the government's ambition to deliver 15,000 new homes in Ebbsfleet.
(CM/JG)
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