The £15m building on Great Homer Street in Everton is part of the Mayor's Investment Plan for Schools, devised as a rescue package following the scrapping of Wave Six of Liverpool's Building Schools for the Future (BSF) project.
The funding – a combination of city council and Government money – was negotiated as part of Liverpool's City Deal, and will see at least 12 schools receive investment.
The school – which will educate up to 1,000 pupils and employs 120 staff, has been built in just over 12 months on a site adjacent to Everton Park Lifestyles Centre. Pupils will use the sports centre for swimming and other activities.
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A community IT and reading space is in development for use by local residents.
Mayor Joe Anderson said: "This is a great moment for the pupils and staff at Notre Dame Catholic College and I am absolutely delighted that it's opening on time and on budget.
"Our young people deserve the very best facilities, and this school showcases some of the latest technology to make sure pupils get the most out of their learning.
"This is the first of at least a dozen substantial investments in education in Liverpool which will transform the experience for tens of thousands of present and future school pupils.
"This signals the start of a significant transformation of this area of North Liverpool, with work getting underway soon on Project Jennifer around Great Homer Street, and our ambitious plans for Everton Park."
The new school is on the edge of the Project Jennifer regeneration scheme which is creating a new district centre around Great Homer Street.
Each classroom has a hi-tech computer system with a large computer touch screen and key pad for each pupil enabling them to actively participate in lessons and answer questions.
(CD/JP)
